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Parallel Crystallizers for Drug Development

Parallel Crystallizers for Drug Development Crystallization research plays an important role in the drug development process as majority of the therapeutic drugs exhibits in multiple polymorph forms and technically each polymorph possess different physical properties. Differences in physical properties (e.g. solubility, hygroscopicity, melting point) would then affect other important properties such as product bioavailability and stability. Pharmaceutical companies worldwide are

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Crystalline PV

Parallel crystallization made visible Parallel Crystallizer with Particle Viewer In addition to providing all the benefits of Technobis’s Crystalline SE (Standard Edition), the Crystalline PV (Particle Viewer) enables automatic determination of particle-size distribution and visualization of all crystallization processes, making it perfect for crystallization process development and optimization. Like other models in the Crystalline range, the PV allows parallel crystallization

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Crystalline RR

Real-time Raman capability in a sophisticated parallel crystallizer Parallel Crystallizer with Raman Probe In addition to providing all the benefits of Technobis’s Crystalline SE (Standard Edition), the advanced Crystalline RR (Raman Ready) incorporates the real-time Raman function. It monitors chemical and morphological changes, providing powerful capabilities in developing and optimizing crystallization processes. Like other models in the Crystalline range, the

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Crystalline SE

Parallel crystallization experimentation made flexible and easy Compact Yet Sophisticated Parallel Crystallizer Technobis’s compact yet sophisticated Crystalline SE (Standard Edition) allows parallel crystallization processes in various modes suitable for crystallization process development and optimization. Its intuitive control and analysis software gives unparalleled access to real-time information on experiments. The Crystalline series meets the needs of a broad range of industries.

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Synthesizer SLTII

Software-driven robotic platform for parallel synthesis workflows Modular robotic platform for automated synthesis Chemspeed’s Synthesizer SLTII is a modular robotic platform enabling automated synthesis on a single platform under virtually any conditions. The versatility of the Synthesizer Platform allows full automation of complete workflows including reagent preparation (liquids and solids), multistep synthesis, workup, purification, analysis and product transfer to storage.

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Crystallization

Crystallization With increasing economic demands, it is becoming progressively more important to gain additional information on drug candidates early in the development cycle. Better informed decision can be made during the selection of candidates if further solid state information is available – saving time and money later on in the development process. But early stage drug candidates are difficult and

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Library

Library Application Notes Chemspeed Technobis Chemspeed AutoPlant Emulsion Polymerizationson the Chemspeed AutoPlant High Output Ruthenium-Catalyzed Hydrogenation of Hexoses High Throughput Drug Profiling Suspensions, slurry transfers and filtration on the Chemspeed MiniPlant SWING Automated, Microwave Assisted Alkene Synthesis via Wittig Reaction Characterization of Medicinal Plants in Traditional Chinese Medicine (TCM) Utilising the substance handling capability of Chemspeed’s Swing platform for library

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Technobis

Technobis Advanced Crystallization Systems Technobis’s advanced crystallization systems are extensively used by the world’s leading pharmaceutical companies. They improve and accelerate crystallization research, making it easy for the user to visualize, understand and control the crystallization process. From preclinical screening to process optimization, Technobis’s systems offer invaluable assistance throughout the various stages of the drug development life cycle. Crystallization Crystal16

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Benchtop Solutions

Application Crystallization With increasing economic demands, it is becoming progressively more important to gain additional information on drug candidates early in the development cycle. Better informed decision can be made during the selection of candidates if further solid state information is available – saving time and money later on in the development process. But early stage drug candidates are difficult

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Analytica

ANALYTICA Munich World’s Leading Trade Fair for laboratory technology, analysis, biotechnology and analytica conference Days Hours Minutes Seconds NIKYANG – ANALYTICA 2020 AUTOMATION AND DIGITALIZATION Innovative automation concepts and digitalization is the core of Laboratory 4.0. How exactly can automation and digitalization optimize the experiments processes and increase R&D efficiency? Check the videos below to see the advanced automation technology

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