Three elements are required for HTS, which include model building, automatic HT sample preparation and sample analysis. Among them, automatic HT sample preparation is critical.
Fig 1: Three elements for HTS
Below is the workflow of HT sample preparation and screening by using microdrop Professional inkjet printing platform. Mouse over the blocks to see an example and videos.
In the workflow above, we need to print many solutions (A-Z). If using the traditional inkjet printing platforms, it needs much more manual operations to clean the heads, change the solutions, and reposition etc, which will lead to low efficiency and unnecessary material consumption and certainly not fit for HT sample preparation. Based on the advantages listed in the following table, microdrop Professional inkjet printing platform is ideal for automatic HT sample preparation.
|Multi-channel||Support up to 8 dispenser heads|
|Auto-pipette||Based on 96-MTP, it is able to change, print, recycle solutions, clean the dispenser head and can print many solutions at one time.|
|Ultra-small volume||Diameter down to 30 μm, volume down to 20 pl, saving materials|
|High accuracy positioning||Positioning accuracy: ±5μm; Repetition accuracy: ±1μm, ensuring sample quality|
|Good stability||Droplets size variation smaller than ±1%, ensuring sample quality|
|In-flight dispensing||Dispensing fast and accurately|
|Automatic dispensing||All procedures can be completed automatically via software programming.|
|Easy operation||Easy to adjust pressure, set parameters and clean dispenser heads|
Using microdrop Professional inkjet printing platform for automatic HT sample preparation and then for HTS can be more economical and efficient to obtain the best results. Actually, this application is not limited to the printed electronics. It can be extended to other researches with many kinds of materials, many parameters and multiple combinations, such as, drug screening, biotechnology, material research, and so on, significantly boosting the research process.