The CAMAG AMD 2 (Automated Multiple Development) procedure allows Thin-Layer Chromatography to be utilized for tasks that could not be performed by TLC in the past. The use of gradient elution gives up to three times the separation power of standard HPTLC, with increased precision and reliability.
In gradient elution the HPTLC plate is developed repeatedly in the same direction, varying the eluent strength each time to give a stepwise elution gradient. This technique results in extremely narrow bands, enabling more components to be resolved, as well as reducing analysis time.